Methods are provided for the treatment and/or prevention of neuronal damage following a CNS insult. Specifically, the methods comprise modulating the cerebral cortex temperature during the recovery phase of a CNS insult and the administration of a neurologic therapeutic agent. The modulation in cerebral temperature is such as to extend the period of time following the CNS insult during which the neurologic therapeutic agent is capable of eliciting a neuroprotective effect.
申请公布号
WO0137855(A2)
申请公布日期
2001.05.31
申请号
WO2000US41591
申请日期
2000.10.26
申请人
CHIRON CORPORATION;GLUCKMAN, PETER, DAVID;GUAN, JIAN;GUNN, ALISTAIR, JAN
发明人
GLUCKMAN, PETER, DAVID;GUAN, JIAN;GUNN, ALISTAIR, JAN