PROGNOSTIC TESTING OF ORGANS INTENDED FOR TRANSPLANTATION

摘要

The present invention discloses a method of prospectively determining whether an organwill function once it is transplanted. A transplantable organ is perfused in an ex vivo warmperfusion system capable of supporting near normal levels of metabolism by the organ. One ormore parameters related to organ function are measured and evaluated during perfusion. Measurements of perfused organ function are compared to values indicative of normal organfunction to obtain a prediction of whether the organ being perfused will function once it has beentransplanted. A method for calculating a viability index based on the parameters evaluated is also disclosed.