发明名称 |
METHOD FOR PRODUCING CELL-FUSION TYPE MORBILLIVIRUS MUTANT |
摘要 |
It is found out that a mutation of an amino acid at a specific position of t he F protein of a morvillivirus induces a decrease in the cell-fusion ability. By introducing this mutation, a virus having a lowered cell-fusion activity can be constructed. Thus, an attenuated virus useful in vaccines can be easily obtained.
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申请公布号 |
CA2392190(A1) |
申请公布日期 |
2001.05.31 |
申请号 |
CA20002392190 |
申请日期 |
2000.10.18 |
申请人 |
THE KITASATO INSTITUTE |
发明人 |
AIZAWA, CHIKARA;KOMASE, KATSUHIRO;NAKAYAMA, TETSUO |
分类号 |
C07K14/115;C12N7/04;C12N15/45;(IPC1-7):C12N15/45;C12N7/00 |
主分类号 |
C07K14/115 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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