发明名称 VACCINATION BY SPECIFIC T-CELL POPULATIONS AGAINST DISEASES CAUSED BY PATHOGENIC RESPONSES
摘要 The invention relates to vaccines and vaccination means of a host with the intention of prevention or controlling specific T-cell determined proliferation diseases. The vaccine is made of pharmaceutically acceptable medium and a segment of T-cell receptor (TCR) found on the surface of the T-cells, determining the disease. The vaccine is applied on the host in a manner which induces an immune response, directed to the TCR of pathogenic T-cells. This immune response regulates or deletes the pathogenic T-cells, and in this way stops of the pathogenesis of the disease. The invention also relates to means for the determination of suitable amino acid sequence for such a vaccine. 6 claims
申请公布号 BG63182(B2) 申请公布日期 2001.05.31
申请号 BG19930097666 申请日期 1993.04.26
申请人 THE IMMUNE RESPONSE CORPORATION 发明人 HOWELL, MARK D.;BROSTOFF, STEVEN W.;CARLO, DENNIS J.
分类号 A61K38/00;C07K14/725;(IPC1-7):A61K38/00 主分类号 A61K38/00
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