发明名称 |
VACCINATION BY SPECIFIC T-CELL POPULATIONS AGAINST DISEASES CAUSED BY PATHOGENIC RESPONSES |
摘要 |
The invention relates to vaccines and vaccination means of a host with the intention of prevention or controlling specific T-cell determined proliferation diseases. The vaccine is made of pharmaceutically acceptable medium and a segment of T-cell receptor (TCR) found on the surface of the T-cells, determining the disease. The vaccine is applied on the host in a manner which induces an immune response, directed to the TCR of pathogenic T-cells. This immune response regulates or deletes the pathogenic T-cells, and in this way stops of the pathogenesis of the disease. The invention also relates to means for the determination of suitable amino acid sequence for such a vaccine. 6 claims
|
申请公布号 |
BG63182(B2) |
申请公布日期 |
2001.05.31 |
申请号 |
BG19930097666 |
申请日期 |
1993.04.26 |
申请人 |
THE IMMUNE RESPONSE CORPORATION |
发明人 |
HOWELL, MARK D.;BROSTOFF, STEVEN W.;CARLO, DENNIS J. |
分类号 |
A61K38/00;C07K14/725;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|