| 摘要 |
The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of: an ophthalmologically active agent containing basic groups, an ion sensitive, hydrophilic polymer containing acidic groups in an amount of 0,004 to 1,5% weight, at least one salt selected from the group of inorganic salts and buffers in a total amount of from 0,01 to 2,0% by weight, and optionally a wetting agent and a preservative, the ratio between salt and polymer being such that the solution exhibits a viscosity of less than 1000mPas, and the pH of the solution is 4,0 to 8,0. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics. 10 claims, 6 figures
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