发明名称 |
CELL PERMEABLE PEPTIDES FOR INHIBITION OF INFLAMMATORY REACTIONS AND METHODS OF USE |
摘要 |
The present invention relates to the delivery of biologically active molecules, such as peptides, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation compete nt signal peptide. Such delivery can be utilized, for example, to treat and/or prevent inflammatory conditions, e.g., but not limited to, systemic inflammatory reactions such as endotoxic shock, localized inflammatory reactions such as inflammatory skin diseases and conditions, and inflammator y diseases such as autoimmune diseases.
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申请公布号 |
CA2391943(A1) |
申请公布日期 |
2001.05.31 |
申请号 |
CA20002391943 |
申请日期 |
2000.11.29 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
HAWIGER, JACK J.;COLLINS, ROBERT D.;TIMMONS, SHEILA;VEACH, RUTH ANN;ROBINSON, DANIEL;LIU, XUE YAN;LIU, DANYA |
分类号 |
A61K38/00;A61K38/17;A61K39/00;A61K47/48;A61P7/00;A61P29/00;A61P31/04;C07K14/475;C07K14/50;C12N15/62;C12N15/87;(IPC1-7):A61K31/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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