| 摘要 |
<p>The invention relates to an oligomer array with PNA (Peptide Nucleic Acid) and/or DNA oligomers on a surface, said oligomers comprising oligomers of 6 to 20 monomers or nucleobases each. Said monomers or nucleobases comprise at least one sequence of the general formula DDCGDD or of the general formula DDTGDD or of the general formula HHCGHH or of the general formula HHCAHH, wherein H represents any of the bases adenine (A), cytosine (C) or thymine (T) and D represents any of the bases adenine (A), guanine (G) or thymine (T). The location of the oligomers on the surface is correlated with the sequence of the oligomers. The inventive oligomer arrays are used to detect cytosine methylations in genomic DNA.</p> |
