CELL PROLIFERATION INHIBITORY PROTEIN, POLYNUCLEOTIDE, ANTISENSE POLYNUCLEOTIDE TO THE POLYNUCLEOTIDE, AND CELL PROLIFERATION INHIBITORS, CANCER DIAGNOSTICS, CANCER REMEDIES AND COMPOSITIONS FOR GENE THERAPY BY USING THE SAME

摘要

A gene showing reduction or disappearance of expression in immortalized cells involving cancer cells is isolated and the DNA sequence thereof is determined. Further, a cell proliferation inhibitory protein is produced by expressing this gene and the gene and the protein are used as diagnostics or remedies to be used in gene diagnosis, gene therapy, etc. for diseases such as cancer.