| 摘要 |
A nucleic acid (as shown in Fig. 1, preferably from nucleotide 132 to 1682) encoding a Drosophila CED-6 (dCED-6) protein with the amino acid sequence shown in Fig. 2 is claimed. Also claimed are expression vectors and transgenic organisms harbouring this sequence, antibodies to epitopes of dCED-6. Methods of identifying compounds that inhibit or enhance phagocytosis of apoptotic cells using dCED-6 or mutated forms thereof are also claimed. |
