发明名称 |
Targeted bifunctional molecules and therapies based thereon |
摘要 |
Targeted bifunctional molecules and methods for their use are provided. The subject targeted bifunctional molecules are conjugates of a drug moiety and a targeting moiety, where these two moieties are optionally joined by a linking group. The bifunctional molecules are further characterized in that they exhibit a modulated biodistribution upon administration to a host as compared to a free drug control. The subject targeted bifunctional molecules find use in a variety of therapeutic applications. |
申请公布号 |
AU2044001(A) |
申请公布日期 |
2001.05.30 |
申请号 |
AU20010020440 |
申请日期 |
2000.11.17 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
ROGER BRIESEWITZ;GERALD R CRABTREE;THOMAS WANDLESS |
分类号 |
A61K31/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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