发明名称 QUINOLINE DERIVATIVES USEFUL FOR INHIBITING FARNESYL PROTEINTRANSFERASE
摘要 The invention relates to compounds of the formula: (see formula I) and to pharmaceutically acceptable salts and solvates thereof wherein Y, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings defined in the specification. The invention also relates to pharmaceutical compositions comprising said compounds and to the use of said compounds for inhibiting abnormal cell growth in mammals. The compounds of t he above formula have activity as farnesyl protein transferase inhibitors.
申请公布号 CA2327026(A1) 申请公布日期 2001.05.30
申请号 CA20002327026 申请日期 2000.11.28
申请人 PFIZER PRODUCTS INC. 发明人 YANG, BINGWEI VERA
分类号 C12N9/99;A61K31/4709;A61P35/00;A61P43/00;C07D401/06;(IPC1-7):C07D401/06;C07D471/04;C07D491/048;C07F7/10;C07D401/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;A61K31/470;A61K31/495;A61K31/53;A61K31/537;A61K31/541;A61K31/695 主分类号 C12N9/99
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