发明名称 |
PROCESS FOR PRODUCING 3-SUBSTITUTED CEPHEM COMPOUND |
摘要 |
<p>A process for producing a 3-substituted cephem compound from an allenyl- beta -lactam compound which can readily be prepared from an inexpensive penicillin compound in a short reaction path. The process comprises reacting an allenyl- beta -lactam compound with an organohalogen compound in the presence of an at least equimolar amount of a metal having a standard oxidation-reduction potential of -0.3 V/SCE or less and 0.0001 - 0.5 mol, per mole of the lactam, of a metallic compound having a standard oxidation-reduction potential higher than that of the above metal.</p> |
申请公布号 |
EP0678520(B1) |
申请公布日期 |
2001.05.30 |
申请号 |
EP19940931679 |
申请日期 |
1994.11.04 |
申请人 |
OTSUKA KAGAKU KABUSHIKI KAISHA |
发明人 |
TORII, SHIGERU;TANAKA, HIDEO;SASAOKA, MICHIO;SHIROI, TAKASHI |
分类号 |
B01J21/02;B01J31/12;C07B61/00;C07D501/00;C07D501/08;C07D501/22;(IPC1-7):C07D501/08;C07D205/095 |
主分类号 |
B01J21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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