发明名称 |
NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES |
摘要 |
<p>The invention concerns a novel method for preparing optically active alpha -aminonitriles of formula (I) by enantioselective hydrocyanation using a hydrocyanation agent, in the presence of a chiral or chirality inducing metal complex acting as catalyst, of ketimines of formula (II) wherein the radicals R1 and R2 and T are such as defined in the description. The invention also concerns the use of alpha -aminonitriles of formula (I) as synthesis intermediates of optically active organic compounds.</p> |
申请公布号 |
EP1102744(A1) |
申请公布日期 |
2001.05.30 |
申请号 |
EP20000940478 |
申请日期 |
2000.06.09 |
申请人 |
AVENTIS CROPSCIENCE S.A. |
发明人 |
BYRNE, JANICE;CHAVAROT, MURIELLE;CHAVANT, PIERRE-YVES;VALLEE, YANNICK;HENRYON, VIVIEN |
分类号 |
C07D233/66;B01J31/02;C07B53/00;C07B61/00;C07C227/32;C07C231/06;C07C231/12;C07C231/18;C07C237/20;C07C253/08;C07C255/42;C07D233/84;C07D317/20;(IPC1-7):C07C253/00 |
主分类号 |
C07D233/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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