发明名称 2-(3,5-BIS-TRIFLUOROMETHYL-PHENYL)-N-METHYL-N-(6-MORPHOLIN-4-YL-4-O-TOLYL-PYRIDIN-3-YL)-ISOBUTYRAMIDE
摘要 The invention relates to the compound of the formula (see formula I) which is 2-(3,5-bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o - tolyl- pyridin-3-yl)-isobutyramide. It has been found that this compound has a high affinity to the NK-1 recepto r and it is therefore useful in the treatment of diseases, which relate to this receptor .
申请公布号 CA2326529(A1) 申请公布日期 2001.05.29
申请号 CA20002326529 申请日期 2000.11.23
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BALLARD, THERESA MARIA;HIGGINS, GUY ANDREW;SLEIGHT, ANDREW;HOFFMANN, TORSTEN;POLI, SONIA MARIA
分类号 C07D213/74;A61K31/5377;A61P1/06;A61P1/08;A61P25/00;A61P25/22;A61P25/24;A61P43/00;C07D213/00;C07D213/75;C07D265/00;C07D413/04;(IPC1-7):C07D213/75;A61P19/02;A61P11/06;A61K31/537 主分类号 C07D213/74
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