ANTIINFLAMMATORY MEDICINAL COMPOSITIONS

摘要

N-[2-(2-Phthalimidoethoxy)acetyl]-L-aranyl-D-glutamic acid which inhibits the production of tumor necrosis factor and interferon- gamma and induces the regulation of cytokine production by, for example, inducing the production of interleukin-10. This compound is useful as remedies for autoimmune diseases such as inflammatory colitis, articular rheumatism, arthrosis deformans, multiple sclerosis, Becet's disease, systemic erythematosus, etc., prurigo, anthema, lupus and inflammatory skin diseases accompanied by sclerosis, multiple organ failure following sepsis, infectious diseases such as AIDS and inflammations accompanying these diseases.