发明名称 |
HYDROXYETHOXYBENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME |
摘要 |
Hydroxyethoxybenzamide derivatives represented by general formula (I), which have a dopamine D2 receptor blocking effect and a 5-HT4 receptor stimulating effect and are useful as drugs ameliorating digestive tract functions with the regulated expression of extrapyramidal syndrome, or pharmacologically acceptable salts thereof; wherein R<1> represents halogeno; R<2> represents hydrogen or halogeno; R<3> represents halogeno; and R<4> represents lower alkyl, lower alkoxy, amino, halo(lower alkyl) or halo(lower alkoxy). These compounds are efficacious for diseases such as reflux esophagitis, epigastric unidentified complaint, gastritis and gastric ulcer.
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申请公布号 |
WO0136385(A1) |
申请公布日期 |
2001.05.25 |
申请号 |
WO2000JP07790 |
申请日期 |
2000.11.07 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD.;OKAZAKI, KOSUKE;KOBAYASHI, HIROAKI;HORA, MASACHIYO;MASUDA, NAOYUKI;KITAZAWA, MAKIO |
发明人 |
OKAZAKI, KOSUKE;KOBAYASHI, HIROAKI;HORA, MASACHIYO;MASUDA, NAOYUKI;KITAZAWA, MAKIO |
分类号 |
A61P1/04;A61P1/08;A61P1/14;A61P43/00;C07D211/58;(IPC1-7):C07D211/58;A61K31/445 |
主分类号 |
A61P1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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