发明名称 |
DIAGNOSTIC METHODS |
摘要 |
The present invention derives from the identification of 26 gene transcripts (Markers) that exhibit aberrant expression levels in prostate disorder tissues. The invention therefore relates to diagnostic techniques for the detection of human prostate disorders, such as cancer, by detecting one or more of these Markers, intermediates, precursors or products (mRNA, cDNA, genomic DNA, or protein). The invention is also directed to methods for identifying modulators of prostate disorders, which modulators, such as chemical compounds, antisense molecules and antibodies interact with and modulate any one of the Markers identified.
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申请公布号 |
WO0136674(A2) |
申请公布日期 |
2001.05.25 |
申请号 |
WO2000GB04267 |
申请日期 |
2000.11.08 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BULL, JOHN, HENRY;ELLISON, GILLIAN;PASKINS, LYNN, DORA |
发明人 |
BULL, JOHN, HENRY;ELLISON, GILLIAN;PASKINS, LYNN, DORA |
分类号 |
A61P43/00;C12Q1/68;G01N33/574;(IPC1-7):C12Q1/68;G01N33/53 |
主分类号 |
A61P43/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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