| 发明名称 |
MOUSE ASPARTIC SECRETASE-2 (mASP-2) |
| 摘要 |
mASP-2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds that either agonize or antagonize mASP-2. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: Alzheimer's disease, cancer and prohormone processing.
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| 申请公布号 |
WO0136600(A1) |
申请公布日期 |
2001.05.25 |
| 申请号 |
WO2000US31583 |
申请日期 |
2000.11.16 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM PLC. |
发明人 |
ZHU, YUAN;LI, XIAOTONG;POWELL, DAVID, J.;CHRISTIE, GARY |
| 分类号 |
A61K38/00;C12N9/64;C12N15/12;(IPC1-7):C12N5/10;C12N15/52;C12N15/63;C12N15/64;G01N33/53;G01N33/567;C07K14/47 |
主分类号 |
A61K38/00 |
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