发明名称 MATERIALS AND METHODS FOR DETECTION AND TREATMENT OF BREAST CANCER
摘要 The invention provides a wide range of methods and compositions for detectin g and treating breast cancer in an individual. Specifically, the invention provides target breast cancer-associated proteins, which permit a rapid detection, preferably before metastases occur, of breast cancer. The target breast cancer-associated protein may be detected, for example, by reacting t he sample with a labeled binding moiety, for example, a labeled antibody capabl e of binding specifically to the protein. The invention also provides kits useful in the detection of breast cancer in an individual. In addition, the invention provides methods utilizing the breast cancer-associated proteins either as targets for treating breast cancer or as indicators for monitoring the efficacy of such a treatment.
申请公布号 CA2390607(A1) 申请公布日期 2001.05.25
申请号 CA20002390607 申请日期 2000.11.16
申请人 MATRITECH, INC. 发明人 WATKINS, BRYNMOR;ZARO, ROBERT P.
分类号 G01N27/62;A61K31/7088;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P35/00;B01D15/04;B01D15/08;C07K14/47;C07K16/18;C12N15/09;C12P21/08;C12Q1/00;C12Q1/68;G01N30/72;G01N30/88;G01N33/48;G01N33/53;G01N33/543;G01N33/566;G01N33/567;G01N33/574;G01N33/577;G01N33/58;G01N33/68;(IPC1-7):C12N15/12;C07K16/30 主分类号 G01N27/62
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