发明名称 Process for the preparation of NMDA antagonists
摘要 <p>A process for the production of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: R1 and R2 are independently phenyl or 4-fluorophenyl; R3 is hydrogen, alkyl or methoxycarbonyl; R4 is hydrogen or methyl; which comprises reaction of a compound of formula (II) with a compound of formula (III), wherein R5-R10 are independently alkyl to give a compound of formula (IV), followed by deprotection and optionally thereafter forming a pharmaceutically acceptable salt.</p>
申请公布号 NZ335870(A) 申请公布日期 2001.05.25
申请号 NZ19970335870 申请日期 1997.12.12
申请人 ASTRAZENECA AB 发明人 HARRIS, ALAN RICHARD
分类号 A61K31/16;C07C231/02;C07C231/12;C07C231/24;C07C235/06;C07C237/06;C07C269/06;C07C271/22;(IPC1-7):C07C231/02 主分类号 A61K31/16
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