| 摘要 |
PROBLEM TO BE SOLVED: To provide an excellent screening method. SOLUTION: This method for screening a compound or its salt capable of changing the affinity of MCH or its salt with SLC-1 or its salt is characterized by using MCH or its derivative or derivative and SLC-1 or its salt. This method is useful as a screening method for SLC-1 agonist usable as a preventive or therapeutic medicine for feeble labor pain, atonic bleeding, placental extraction, uterus subinvolution, caesarean section, artificial abortion, lacteal retention or the like in addition to an appetite (ingestion) improver, and SLC-1 antagonist usable as a preventive or therapeutic medicine for hyperdynamia uteri, tonic uterus contraction, fetal distress, hysterorrhexis, cervical rupture, immature birth, Prader-Willi symptoms or the like in addition to an anti-obese agent (medicine), appetite (ingestion) regulating agent or the like. |
