| 摘要 |
<p>The invention provides a poly(diallylamine) polymer derived from a monomer of formula (I) wherein R6 is a bridging group of valency r and r is an integer of 3 or greater, or a pharmaceutically acceptable derivative of such a polymer, for use in any surgical, therapeutic or diagnostic method, in particular for use as a bile acid remover and/or for use in reducing serum cholesterol levels. The invention also provides the use of such a polymer or derivative in the preparation of a medicament for use in any surgical, therapeutic or diagnostic method, in particular where the medicament is a bile acid remover or is for use in reducing serum cholesterol levels. The invention further provides a method of treatment of a human or animal patient to reduce levels of bile acid and/or serum cholesterol, by administering such a polymer; a pharmaceutical composition containing the polymer; and a method for producing the pharmaceutical composition.</p> |
