| 发明名称 |
Anticoagulant peptidyl-arginine aldehyde derivatives |
| 摘要 |
The invention relates to new peptidyl-arginine aldehyde compounds of formula (I)whereinQ represents an acyl group of formula Q'-OCO, wherein Q' represents an alkyl-group with 1-3 carbon atoms,D-Xaa represents a 3-cyclobutyl-D-alanyl- or 3-cyclopentyl-D-alanyl group,Pro represents an L-prolyl group, andArg represents an L-arginyl group,and acid-addition salts thereof, and pharmaceutical compositions comprising them, which are suitable for the prevention and cure of thrombosis and accelerated blood clotting.
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| 申请公布号 |
US6235707(B1) |
申请公布日期 |
2001.05.22 |
| 申请号 |
US19980194124 |
申请日期 |
1998.11.23 |
| 申请人 |
GYOGYSZERKUTATO INTEZET KFT. |
发明人 |
BAJUSZ SáNDOR;JUHáSZ ATTILA;BARABáS éVA;FEHéR ANDRáS;SZABO GABRIELLA;SZéLL NéE HASENOEHRL ERZSéBET;VéGHELYI NéE FAUSZT IRéN;LAVICH NéE OSZKO EMILIA;KASZáS éVA;LANGO JOZSEF;MORAVCSIK IMRE;SZEKER NéE PESZEKY áGNES;TASCHLER NéE PáSZTOR ZSUZSANNA;TOTH GáBOR;MOHAI NéE NAGY ZSUZSANNA;SZALKAY NéE HOLLOSI ANNA MáRIA;MAKK NéE OCSKAY KLáRA |
| 分类号 |
A61K38/00;A61K31/00;A61P7/00;A61P7/02;C07K5/06;C07K5/065;(IPC1-7):C07K5/08;A61K38/06 |
主分类号 |
A61K38/00 |
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