发明名称 Fused imidazopyridine derivatives as antihyperlipidemic agents
摘要 A novel compound of the formula:wherein ring Q is an optionally substituted pyridine ring;One of R0, R1 and R2 is -Y0-Z0, and the other tow groups are a hydrogen, a halogen, an optionally substituted hydroxy group, a hydrocarbon group that may be an optionally substituted hydrocarbon group or an acyl group;Y0 is a bond or an optionally substituted bivalent hydrocarbon group;Z0 is a basic group which may be bonded via oxygen, nitrogen, -CO-, -CS-, -SO2N(R3)- (where R3 is hydrogen or an optionally substituted hydrocarbon group), or S(O)n (wherein n is to 0, 1 or 2);......... is a single bond or a double bond, or a salt thereof, which has an excellent LDL receptor up-regulating, blood-lipids lowering, blood-sugar lowering and diabetic complication-ameliorating activity.
申请公布号 US6235731(B1) 申请公布日期 2001.05.22
申请号 US19980155889 申请日期 1998.10.08
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SHIBOUTA YUMIKO;SUGIYAMA YASUO;KAWAMOTO TETSUJI;TAKATANI MUNEO
分类号 C07D513/16;(IPC1-7):A61K31/549;C07D513/18 主分类号 C07D513/16
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