发明名称 Process for the separation of a mixture of enantiomers
摘要 A diastereomer complex obtained via a process for the separation of enantiomers is disclosed, wherein separation can be rapidly effected such that enantiomers are obtained with high e.e. values. The process pets the separation of mixtures of enantiomers in which more than one resolving agent is used, of which at least one resolving agent is optically active, and which yields a diastereomer complex containing at least two resolving agents in optically active form. The process provides for, inter alia, a diastereomer complex having at least three compounds of which at least two compounds are resolving agents in optically active form, and at least one compound is an onantiomer in optically active form. Also provided is a diastereomer complex having at least three compounds of which at lea one compound is a resolving agent in optically active form, and at least two compounds which are enantiomers in optically active form.
申请公布号 US6235927(B1) 申请公布日期 2001.05.22
申请号 US19970955612 申请日期 1997.10.22
申请人 DSM N.V. 发明人 VRIES TON R.;WIJNBERG HANS;VAN ECHTEN ERIK;HULSHOF LUMBERTUS A.;BROXTERMAN QUIRINUS B.
分类号 C07D233/32;C07B57/00;C07C51/487;C07C209/80;C07C209/88;C07C211/27;C07C211/28;C07C211/29;C07C211/39;C07C213/10;C07C215/08;C07C215/44;C07C215/50;C07C217/50;C07C227/34;C07C227/40;C07C229/34;C07C229/36;C07C253/34;C07C255/42;C07C309/23;C07C309/24;C07D207/06;C07D207/08;C07D211/22;C07D265/30;C07D295/023;C07D317/20;C07D317/22;C07D471/04;C07F9/6574;(IPC1-7):C07B55/00 主分类号 C07D233/32
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