发明名称 COMPOSITION FOR DELIVERING COMPOUND AND ACTIVATOR
摘要 PROBLEM TO BE SOLVED: To provide a carrier compound and a composition thereof for delivering activators, the administrations including the oral route and the like, and the preparation method thereof. SOLUTION: The objective composition comprises (A) at least one of activator and (B) a compound represented by formula (1) or the salts thereof and the single dose unit including the composition. The activation agent includes at least peptide, muco-polysaccharide, carbohydrate or lipid. For exarnple, it is selected from the group consisting of human growth hormone, bovine growth hormone, growth hormone-releasing hormone, interferons, interleukin-I, interleukin-II, insulin, heparin, low molecular-weight heparin, calcitonin, erythropoietin, atrial natriuretic polypeptide, antigens, monoclonal antibodies, somatostatin, somatostatin, adenocorticotropin, gonadotropin-releasing hormone, oxytocin, vasopressin, cromolyn sodium, vancomycin, deferoxamine, parathyroid hormone and their combinations.
申请公布号 JP2001139494(A) 申请公布日期 2001.05.22
申请号 JP20000311230 申请日期 2000.10.11
申请人 EMISPHERE TECHNOLGIES INC 发明人 LEONE-BAY ANDREA;HO KOC-KAN;LEIPOLD HARRY R;MILSTEIN SAM J;SARUBBI DONALD J;WANG ERIC;DAVID GUSHUNAIDAA
分类号 A61K47/16;A61K9/08;A61K9/16;A61K9/20;A61K9/48;A61K31/16;A61K31/195;A61K31/352;A61K31/70;A61K31/7052;A61K31/726;A61K31/727;A61K38/00;A61K38/04;A61K38/11;A61K38/21;A61K38/22;A61K38/23;A61K38/27;A61K38/28;A61K38/29;A61K39/00;A61K39/395;A61K45/00;A61K45/06;A61K47/12;A61K47/18;A61K47/20;A61K47/22;A61P5/00;A61P43/00;C07C229/42;C07C233/51;C07C233/54;C07C233/69;C07C233/81;C07C233/83;C07C235/12;C07C235/24;C07C235/34;C07C235/38;C07C235/52;C07C235/56;C07C235/60;C07C235/64;C07C235/66;C07C235/74;C07C237/12;C07C237/20;C07C237/36;C07C237/40;C07C237/42;C07C243/38;C07C259/06;C07C271/28;C07C271/54;C07D209/48;C07D211/62;C07D213/81;C07D213/82;C07D239/42;C07D241/24;C07D257/04;C07D295/18;C07D295/192;C07D311/12;C07D311/24;C07D311/30;(IPC1-7):A61K47/16 主分类号 A61K47/16
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