发明名称 |
Efficient ex vivo expansion of CD4+ and CD8+ T-cells from HIV infected subjects. |
摘要 |
Methods for the expansion of CD4, CD8, and DP T-cells from HIV infected patients are disclosed which allow the maintenance of low levels of HIV. The invention further discloses methods for the inhibition of HIV gene expression. Also disclosed are methods for the rapid and efficient screening of cells derived from HIV-infected patients to assess the suitability of various antiviral treatments. The invention further provides a means for the generation of cell banks for use in immune reconstitution and means of treating or modifying expanded cell populations prior to infusion to enhance or modulate therapeutic effectiveness. |
申请公布号 |
ZA200006837(B) |
申请公布日期 |
2001.05.22 |
申请号 |
ZA20000006837 |
申请日期 |
2000.11.22 |
申请人 |
HEMOSOL INC. |
发明人 |
DAVID BELL;KENNETH ROSENTHAL |
分类号 |
A61K35/12;A61K38/00;C12N5/00;C12N5/0783 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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