Semiconductor nanoparticles for analysis of blood cell populations and methods of making same

摘要

A semiconductor nanoparticle for use in analysis of biological samples is described. This semiconductor nanoparticle is composed of an aminodextran which is bound to at least one nanoparticle of the formula (X Y)n wherein X is selected from the group comprising Cd2+, Hg2+, and Zn2+ and combinations thereof; and Y is selected from the group comprising S2-, Se2- and Te2- and combinations thereof; and n=approximately 50 to 1000. Also provided are methods of making these semiconductor nanoparticles and methods of making conjugates composed of these semiconductor nanoparticles linked to ligands. Also described are uses for the conjugates in a variety of biological assays.