5-ARYL-1H-1,2,4-TRIAZOLE COMPOUNDS AS INHIBITORS OF CYCLOOXYGENASE-2 AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

The invention relates to 5-aryl-1H-1,2,4-triazole compounds of formula (I) in which R?1, R2, R3 and R4¿ are as defined in the specification.These compounds are potent and selective COX-2 inhibitors.The invention also relates to pharmaceutical compositions comprising these compounds.