SOLID DISPERSION PHARMACEUTICAL FORMULATIONS

摘要

A pharmaceutical composition is disclosed which comprises a soliddispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compress ed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersio n and methods of treating an HIV infection employing said solid dispersion.