发明名称 |
METHODS OF TREATING SHORT STATURE DISORDERS RELATED TO THE SHORT STATURE HOMEOBOX-CONTAINING (SHOX) GENE |
摘要 |
The invention relates to methods and articles of manufacture for treating short stature disorders related to the Short Stature Homeobox-containing (SHOX) gene which, in the human genome, is located in the pseudoautosomal region (PAR1) on the short arm of the X chromosome (Xp22.3) and Y chromosome (Yp11.3). More particularly, the invention relates to methods for treating a SHOX gene disorder, other than Turner syndrome, due to deficiency of one copy (haploinsufficiency) of the SHOX gene, by administering a growth hormone, particularly by administering human growth hormone to a human subject with a SHOX gene disorder.
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申请公布号 |
WO0134181(A2) |
申请公布日期 |
2001.05.17 |
申请号 |
WO2000IB01612 |
申请日期 |
2000.11.08 |
申请人 |
RAPPOLD-HOERBRAND, GUDRUN;RAO, ERCOLE |
发明人 |
RAPPOLD-HOERBRAND, GUDRUN;RAO, ERCOLE |
分类号 |
A61K38/27;A61P5/06;A61P19/00;(IPC1-7):A61K38/27 |
主分类号 |
A61K38/27 |
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