METHODS FOR TREATING, INHIBITING OF PREVENTING PATHOGENIC CHANGE RESULTING FROM VASCULAR INJURY WITH AN ALDOSTERONE ANTAGONIST

摘要

The present invention provides methods of treating, inhibiting or preventing pathogenic change resulting from vascular injury in a subject, particularly restenosis resulting substantially from angioplasty. The methods comprise administering a therapeutically-effective amount of an aldosterone antagonis t, particularly eplerenone, in a mammalian subject susceptible to or suffering from said pathogenic change.