发明名称 A pharmaceutical formulation containing growth hormone, an amino acid and a non-ionic detergent
摘要 The invention relates to pharmaceutical formulations comprising human growth hormone, an amino acid selected from the group of Asp, Ile, Val, Leu or His, or a derivative of histidine and a non-ionic detergent, eg. polysorbate or poloxamer. The formulation is stabilized against deamidation and aggregation. The formulation may be an aqueous formulation.
申请公布号 AU733592(B2) 申请公布日期 2001.05.17
申请号 AU19970026343 申请日期 1997.04.24
申请人 NOVO NORDISK A/S 发明人 SOREN BJORN;HANS HOLMEGAARD SORENSEN;PETER LANGBALLE;SILKE MOLLER LARSEN;KIRSTEN EBBEHOJ;BIRTHE LYKKEGAARD HANSEN
分类号 A61K9/08;A61K31/00;A61K38/00;A61K38/27;A61K47/10;A61K47/18;A61K47/26;A61K47/34;A61P1/00;A61P5/00;A61P5/06;A61P15/00;A61P17/00;A61P17/02;A61P19/00;A61P19/02;A61P19/10;A61P21/00;A61P21/04;(IPC1-7):A61K38/27 主分类号 A61K9/08
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