发明名称 |
A pharmaceutical formulation containing growth hormone, an amino acid and a non-ionic detergent |
摘要 |
The invention relates to pharmaceutical formulations comprising human growth hormone, an amino acid selected from the group of Asp, Ile, Val, Leu or His, or a derivative of histidine and a non-ionic detergent, eg. polysorbate or poloxamer. The formulation is stabilized against deamidation and aggregation. The formulation may be an aqueous formulation. |
申请公布号 |
AU733592(B2) |
申请公布日期 |
2001.05.17 |
申请号 |
AU19970026343 |
申请日期 |
1997.04.24 |
申请人 |
NOVO NORDISK A/S |
发明人 |
SOREN BJORN;HANS HOLMEGAARD SORENSEN;PETER LANGBALLE;SILKE MOLLER LARSEN;KIRSTEN EBBEHOJ;BIRTHE LYKKEGAARD HANSEN |
分类号 |
A61K9/08;A61K31/00;A61K38/00;A61K38/27;A61K47/10;A61K47/18;A61K47/26;A61K47/34;A61P1/00;A61P5/00;A61P5/06;A61P15/00;A61P17/00;A61P17/02;A61P19/00;A61P19/02;A61P19/10;A61P21/00;A61P21/04;(IPC1-7):A61K38/27 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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