| 摘要 |
1315735 N(6) - (2,5 - dimethyl - benzyl) - 2- chloroadenosine BOEHRINGER MANNHEIM GmbH 4 Nov 1971 [10 Nov 1970] 51344/71 Heading C2C Novel compound of the formula is prepared by reacting triacetyl-2,6-dichloro-9- (#-D-ribofuranosyl)-purine with 2,5-dimethylbenzylamine in the presence of a weak base (preferably triethylamine) and subsequently saponifying the triacetyl groups preferably using ammoniacal alcohol. The above compound is active against atherosclerosis and with an adjuvant forms a pharmaceutical composition which may be administered orally or parenterally. |
