发明名称 |
CROSSLINKING OF BIOPROSTHETIC MATERIAL TO MITIGATE POST-IMPLANTATION CALCIFICATION |
摘要 |
<p>A method for fixation of biological tissues, and bioprosthetic devices prepared by such method. The method generally comprises the steps of A) fixing the tissue, B) treating the tissue with a mixture of i) a denaturant, ii) a surfactant and iii) a crosslinking agent, C) fabricating or forming the bioprosthesis (e.g., forming the tissue and attaching any non-biological components thereto) and D) subjecting the bioprosthesis to terminal sterilization.</p> |
申请公布号 |
EP1098670(A1) |
申请公布日期 |
2001.05.16 |
申请号 |
EP19990948339 |
申请日期 |
1999.09.20 |
申请人 |
EDWARDS LIFESCIENCES CORPORATION |
发明人 |
CUNANAN, CRYSTAL, M.;QUINTERO, LILLIAN;HELMUS, MICHAEL, N.;LOSHBAUGH, CHRISTINE;SARNER, CHRIS, H. |
分类号 |
A61L27/00;A61L27/36;A61L33/00;A61L33/12;(IPC1-7):A61L27/24 |
主分类号 |
A61L27/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|