发明名称 VIBRIO CHOLERAE VACCINE CANDIDATES AND METHODS OF THEIR CONSTRUCTING
摘要 <p>Vibrio cholerae vaccine strains which have a disrupted hap gene and which are tagged with celA coding functions from Clostridium thermocellum are described. A contained, genetically defined thyA mutant of Vibrio cholerae and the general methodology of making along with the sequence of thyA gene are also described.</p>
申请公布号 EP1099759(A2) 申请公布日期 2001.05.16
申请号 EP19980964347 申请日期 1998.12.30
申请人 CENTRO NACIONAL DE INVESTIGACIONES CIENTIFICAS 发明人 CAMPOS GOMEZ, JAVIER;FANDO CALZADA, RAFAEL ALFREDO;RODRIGUEZ GONZALEZ, BORIS LUIS;LEDON PEREZ, TALENA YAMILE;VALLE DIAZ, EDGAR;SILVA CABRERA, ANISIA JUANA;BENITEZ ROBLES, JORGE ANTONIO
分类号 C12N1/21;C12N15/09;A61K39/106;A61P31/04;C12N9/10;C12N9/52;C12N15/31;C12R1/63;(IPC1-7):C12N15/31 主分类号 C12N1/21
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