发明名称 |
NOVEL 9-(3,5-DIMETHOXYPHENYL)-5,8,8A,9-TETRA -HYDRO[3',4':6,7]NAPHTO[2,3-D] [1,3]DIOXOLE-6(5AH)-ONE, PRODUCTION THEREOF AND MEDICINAL COMPOSITION CONTAINING THE SAME |
摘要 |
<p>PROBLEM TO BE SOLVED: To provide a novel compound, 9-(3,5-dimethoxy-phenyl)-5,8,8a,9-tetra- hydro [3',4':6,7]-naphto [2, 3-d] [1,3]-dioxole-6(5aH)-one, that has high activity in the anti-tumor therapy with high solubility and high tolerance and is useful as a novel antitumor agent and a novel cytotoxic agent. SOLUTION: The novel compound is represented by formula (I) [where R is a group of formula (i) and formula (ii); X and Y are each H or the like; W is H or the like; A is a single bond or the like, G is H and the like; R1 is H or the like]. The production process of the novel compound and pharmaceutical preparation containing the same are provided.</p> |
申请公布号 |
JP2001131182(A) |
申请公布日期 |
2001.05.15 |
申请号 |
JP20000325210 |
申请日期 |
2000.10.25 |
申请人 |
ADIR |
发明人 |
MONNERET CLAUDE;BERTOUNESQUE EMMANUEL;MERESSE PHILIPPE;ATASSI GHANEM;PIERRE ALAIN;PFEIFFER BRUNO;RENARD PIERRE |
分类号 |
C07D493/06;A61K31/357;A61K31/36;A61K31/365;A61K31/70;A61P35/00;C07B61/00;C07D493/04;C07D519/00;C07H17/04;(IPC1-7):C07D493/04 |
主分类号 |
C07D493/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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