发明名称 |
Process for the production of heparin |
摘要 |
The invention relates to a simplified process for the extraction of heparin from animal mucosa tissue. The method consists of an enzymatic hydrolysis step of the raw material at ambient temperature, followed by hydrolysis for up to 6 hours at a temperature of 50-75° C. Raise in temperature is obtained by easy means. The digestion mixture can be further incubated while cooling down to ambient temperature. Heparin is recovered from anion exchanger present in the protein hydrolysate.
|
申请公布号 |
US6232093(B1) |
申请公布日期 |
2001.05.15 |
申请号 |
US20000462223 |
申请日期 |
2000.01.03 |
申请人 |
AKZO NOBEL N.V. |
发明人 |
VAN HOUDENHOVEN FRANCOIS EGBERT ABRAHAM;SANDERS ADRIANUS LAMBERTUS MARIA;VAN ZUTHPEN PETRUS JOHANNES JOSEPHUS |
分类号 |
C08B37/10;C08B37/00;(IPC1-7):C12P21/06 |
主分类号 |
C08B37/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|