PRODUCING METHOD OF ALPHA-KETOCARBOXYLIC ACID DERIVATIVES

摘要

PURPOSE: A process for preparing alpha-ketocarboxylic acid derivatives by reacting alpha-hydroxycarboxylic acid derivatives with hypobromous acid(HOBr) is provided, which is industrially useful by using hypobromous acid in place of an oxidant that is expensive and harmful to environment. CONSTITUTION: The titled alpha-ketocarboxylic acid derivatives of formula 1 is prepared by reacting alpha-hydroxycarboxylic acid derivatives with hypobromous acid as an oxidant at -5 to 40deg.C, wherein the hypobromous acid is used in the range of 1 to 2 molar equivalent based on the compound of formula 2.