发明名称 |
Composite nanospheres and their conjugates with biomolecules |
摘要 |
The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting of an organic phase and inorganic nanoparticles, distributed inside the organic phase, and a skin consisting of at least a hydrophilic polymer derived from the polymerisation of at least one water soluble monomer, in particular N-alkylacrylamide or a N-N-dialkylacrylamide; conjugates derived from said nanospheres; their preparation methods and their uses. |
申请公布号 |
AU1288201(A) |
申请公布日期 |
2001.05.14 |
申请号 |
AU20010012882 |
申请日期 |
2000.11.06 |
申请人 |
BIO MERIEUX;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;OLIVIER MONDAIN-MONVAL |
发明人 |
ABDELHAMID ELAISSARI;ERIC BOSC;CHRISTIAN PICHOT;BERNARD MANDRAND;JEROME BIBETTE |
分类号 |
G01N33/545;A61K9/51;A61K31/7088;A61K45/00;A61K47/02;A61K47/04;A61K47/32;A61K47/48;A61K48/00;A61P43/00;C09D11/00;G01N33/543 |
主分类号 |
G01N33/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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