| 发明名称 |
Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same |
| 摘要 |
The present invention is directed to nucleic acid sequences and the polypeptides encoded thereby that are differentially expressed in angiogenesis. Also provided are methods for stimulating or inhibiting angiogenesis in mammals, including humans. Pharmaceutical compositions based on polypeptides, agonists, or antagonists thereto are also provided. Additionally, the invention also provides methods for diagnosing and treating angiogenic disorders including, but not limited to, wound healing and cancer. |
| 申请公布号 |
AU1449301(A) |
申请公布日期 |
2001.05.14 |
| 申请号 |
AU20010014493 |
申请日期 |
2000.11.01 |
| 申请人 |
CURAGEN CORPORATION;GENENTECH INC. |
发明人 |
FUAD MEHRABAN;MARY GERRITSEN;LUCA RASTELLI |
| 分类号 |
G01N33/53;A61K31/7088;A61K38/16;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P15/00;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07K14/47;C07K14/705;C07K16/28;C12M1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;C12Q1/68;G01N33/566 |
主分类号 |
G01N33/53 |
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