| 摘要 |
PROBLEM TO BE SOLVED: To arrange a double stranded nucleic acid on a substrate having a smooth surface in the state where all the base pairs thereof are exposed upward. SOLUTION: An intercalation reagent which can be inserted between the base pairs of the double stranded nucleic acid to rewind the double spiral structure of the double stranded nucleic acid is reacted with the double stranded nucleic acid, and the spiral structure of the double stranded nucleic acid is solved to parallelize the double chain, whereby all the base pairs of the double stranded nucleic acid are oriented on one side of the reference surface of the parallelized double stranded nucleic acid. The thus-parallelized double stranded nucleic acid is arranged on a substrate having a smooth surface with the base pairs upward.
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