发明名称 |
NOVEL CYCLOPROPANES AS CGRP ANTAGONISTS, MEDICAMENTS CONTAINING SAID COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF |
摘要 |
The invention relates to compounds of the general formula (I), in which R an d R1 are defined as in claim 1. The invention also relates to their tautomers, diastereomers and enantiomers, to mixtures thereof and to their salts, especially to their physiologically acceptable salts with inorganic or organ ic acids or bases. The inventive compounds have valuable pharmacological properties, including CGRP antagonist properties. The invention further relates to medicaments that contain said compounds, to the use and the production thereof.
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申请公布号 |
CA2387134(A1) |
申请公布日期 |
2001.05.10 |
申请号 |
CA20002387134 |
申请日期 |
2000.10.21 |
申请人 |
BOEHRINGER INGELHEIM PHARMA KG |
发明人 |
HALLERMAYER, GERHARD;BAUER, ECKHART;ENGEL, WOLFHARD;EBERLEIN, WOLFGANG;RUDOLF, KLAUS;DOODS, HENRI |
分类号 |
A61K31/454;A61K31/4545;A61K31/4745;A61K31/517;A61K31/519;A61K31/5377;A61P3/10;A61P5/24;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P29/00;A61P37/08;A61P39/02;A61P43/00;C07D401/04;C07D405/14;C07D471/04;(IPC1-7):C07D401/04;A61K31/445 |
主分类号 |
A61K31/454 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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