发明名称 NOVEL CYCLOPROPANES AS CGRP ANTAGONISTS, MEDICAMENTS CONTAINING SAID COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
摘要 The invention relates to compounds of the general formula (I), in which R an d R1 are defined as in claim 1. The invention also relates to their tautomers, diastereomers and enantiomers, to mixtures thereof and to their salts, especially to their physiologically acceptable salts with inorganic or organ ic acids or bases. The inventive compounds have valuable pharmacological properties, including CGRP antagonist properties. The invention further relates to medicaments that contain said compounds, to the use and the production thereof.
申请公布号 CA2387134(A1) 申请公布日期 2001.05.10
申请号 CA20002387134 申请日期 2000.10.21
申请人 BOEHRINGER INGELHEIM PHARMA KG 发明人 HALLERMAYER, GERHARD;BAUER, ECKHART;ENGEL, WOLFHARD;EBERLEIN, WOLFGANG;RUDOLF, KLAUS;DOODS, HENRI
分类号 A61K31/454;A61K31/4545;A61K31/4745;A61K31/517;A61K31/519;A61K31/5377;A61P3/10;A61P5/24;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P29/00;A61P37/08;A61P39/02;A61P43/00;C07D401/04;C07D405/14;C07D471/04;(IPC1-7):C07D401/04;A61K31/445 主分类号 A61K31/454
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