发明名称 |
Assay for methylation in the GST-Pi Gene. |
摘要 |
A diagnostic or prognostic assay is disclosed for a disease or condition characterised by abnormal methylation of cytosine at a site or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g. prostate cancer and liver cancer). The assay comprises;
(i) isolating DNA from said subject, and
(ii) determining (e.g. by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences. |
申请公布号 |
ZA200006803(B) |
申请公布日期 |
2001.05.10 |
申请号 |
ZA20000006803 |
申请日期 |
2000.11.21 |
申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION |
发明人 |
SUSAN JOY CLARK;DOUGLAS S MILLAR;PETER LAURENCE MOLLOY |
分类号 |
C12N15/09;C12N9/10;C12N15/54;C12Q1/48;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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