PROTEASE INHIBITORS AS MODULATORS OF PERIODONTAL WOUND HEALING

摘要

The invention relates to methods for regulating periodontal tissue formation , particularly periodontal tissue attachment, utilising plasminogen activator inhibitors or functional derivatives, equivalents, homologues, analogues or mimetics thereof are described. Further, the invention provides methods for the therapeutic and/or prophylactic treatment of conditions necessitating th e up-regulation, inducement or other enhancement of periodontal wound healing such as gingivitis, periodontitis or following gum injuries, and composition s suitable for use in said methods.