发明名称 |
GENE EXPRESSION DIRECTED BY A SUPER-PSA PROMOTER |
摘要 |
The present invention provides methods and compositions for the delivery and expression of therapeutic genes for treating prostate and non-prostate tumor s in a gene therapy setting with therapeutic genes driven by a super PSA promoter. This approach enhances the capability of increasing the size of therapeutic gene inserts and maintaining specificity and efficiency of genes expression. This form of gene therapy strategy can be applied either alone o r in combination with other adjuvant therapies or used in combination with various gene therapy strategies to achieve the maximum effect in cancer treatment, and in normal and benign tissues to enhance therapeutic gains.</S DOAB>
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申请公布号 |
CA2389335(A1) |
申请公布日期 |
2001.05.10 |
申请号 |
CA20002389335 |
申请日期 |
2000.10.26 |
申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
YEUNG, FAN;CHUNG, LELAND W.K.;KAO, CHINGHAI;TRAPMAN, JAN |
分类号 |
A01K67/027;A61K31/711;A61K35/12;A61K48/00;A61P13/08;A61P35/00;A61P43/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;G01N33/574;(IPC1-7):C07H21/02;A01N43/04;C07H21/04;C12N15/00;C12N15/63;C12Q1/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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