| 发明名称 |
SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 |
| 摘要 |
<p>A class of substituted beta -amino acids are potent inhibitors of methionine aminopeptidase type 2 (MetAP2) and are thus useful in inhibiting angiogenesis and disease conditions which depend upon angiogenesis for their development such as diabetic retinopathy, tumor growth, and conditions of inflammation. Pharmaceutical compounds containing the compounds and methods of inhibiting methionine aminopeptidase-2, and angiogenesis are also disclosed.</p> |
| 申请公布号 |
SK16282000(A3) |
申请公布日期 |
2001.05.10 |
| 申请号 |
SK20000001628 |
申请日期 |
1999.04.30 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
CRAIG RICHARD A.;HENKIN JACK;KAWAI MEGUMI;LYNCH LINDA LIJEWSKI;PATEL JYOTI;SHEPPARD GEORGE S.;WANG JIEYI |
| 分类号 |
C07C235/16;C07C237/12;C07C237/14;C07C311/18;C07C311/19;C07C323/58;C07C323/60;C07D207/26;C07D207/27;C07D209/14;C07D209/48;C07D211/58;C07D211/62;C07D211/70;C07D213/40;C07D213/74;C07D213/75;C07D217/06;C07D231/40;C07D233/76;C07D233/95;C07D235/14;C07D241/08;C07D277/46;C07D277/56;C07D295/185;C07D307/14;C07D317/58;C07D317/66;C07D333/20;C07D333/38;C07D521/00;(IPC1-7):C07C323/60;A61K31/16 |
主分类号 |
C07C235/16 |
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