摘要 |
<p>A miniaturized ion sprayer device is suitable for coupling with chip-based analytical separation devices, multi-well plates, or surfaces containing residues of prepared samples. One embodiment is a 'micro sprayer' device, which is suitable for coupling to the terminal edge of a capillary electrophoresis (CE) chip, is constructed from a modified HPLC tubing and associated fittings and employs a free-standing liquid junction formed via continuous delivery of a flow (1-6 microliters/min) of suitable solvent, which carries effluent through a pneumatically-assisted electrospray (ion spray) needle.</p> |