发明名称 USE OF A HMG-COA REDUCTASE INHIBITOR FOR TREATING AMYLOID BETA PRECURSOR DISORDERS
摘要 <p>Methods for the treatment and prevention of APP processing disorders such as Alzheimer's disease and Down's Syndrome which are based on the administration of an effective amount of a HMG-CoA reductase inhibitor to a mammal are disclosed. Additionally, methods for the treatment and prevention of APP processing disorders such as Alzheimer's disease and Down's Syndrome which are based on the reduction of cellular cholesterol in a mammal are disclosed. These methods reduce the amount of Aβ peptides or decrease the formation of Aβ peptides or increase the clearance of Aβ peptides in a mammal suffering from Alzheimer's disease and Down's Syndrome.</p>
申请公布号 WO2001032161(A2) 申请公布日期 2001.05.10
申请号 US2000041841 申请日期 2000.11.03
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