摘要 |
<p>A method of screening a large population of variant cells or cell colonies present on a first surface, which cells or colonies may be capable of producing a useful polypeptide, RNA or small molecule, which method comprises the steps of i) on the first surface, subjecting the cells or cell colonies to an assay correlated to a property of the useful polypeptide, RNA or small molecule; ii) by means of a colony picker, selecting cells having the property from the first surface; and iii) transferring the selected cells to a second surface.</p> |